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A novel bispecific molecule delivered by recombinant AAV2 suppresses ocular inflammation and choroidal neovascularization

Elevated vascular endothelial growth factor (VEGF) and complement activation are implicated in the pathogenesis of different ocular diseases. The objective of this study was to investigate the hypothesis that dual inhibition of both VEGF and complement activation would confer better protection again...

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Bibliografiska uppgifter
I publikationen:J Cell Mol Med
Huvudupphovsmän: Li, Yiming, Zhu, Ping, Verma, Amrisha, Prasad, Tuhina, Deng, Hongxin, Yu, Dechao, Li, Qiuhong
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543459/
https://ncbi.nlm.nih.gov/pubmed/28332318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13086
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