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Locoregional therapy with α‐emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2‐positive gastric cancer in mice

Peritoneal metastasis of gastric cancer (PMGC) is incurable and thus has an extremely poor prognosis. We have found, however, that locoregionally administered trastuzumab armed with astatine‐211 ((211)At‐trastuzumab) is effective against human epidermal growth factor receptor 2 (HER2)‐positive PMGC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Li, Huizi Keiko, Morokoshi, Yukie, Nagatsu, Kotaro, Kamada, Tadashi, Hasegawa, Sumitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543454/
https://ncbi.nlm.nih.gov/pubmed/28514062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13282
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