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Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells

Retinoic acid (RA) induces cell cycle arrest and differentiation of human neuroblastoma (NB) cells. Typically, NB cells differentiate along the neuronal lineage, but quiescent, “flat” cell types frequently have been described after treatment with differentiating agents. Two indistinguishable subclon...

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Detalles Bibliográficos
Autores principales: Wainwright, Linda J., Lasorella, Anna, Iavarone, Antonio
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55432/
https://ncbi.nlm.nih.gov/pubmed/11481496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161288698
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