Activation of Wnt/β‐catenin signalling is required for TGF‐β/Smad2/3 signalling during myofibroblast proliferation

Fibrosis in animal models and human diseases is associated with aberrant activation of the Wnt/β‐catenin pathway. Despite extensive research efforts, effective therapies are still not available. Myofibroblasts are major effectors, responsible for extracellular matrix deposition. Inhibiting the proli...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Xu, Liang, Cui, Wen‐Hui, Zhou, Wen‐Cheng, Li, De‐Lin, Li, Liu‐Cheng, Zhao, Ping, Mo, Xiao‐Ting, Zhang, Zhihui, Gao, Jian
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542906/
https://ncbi.nlm.nih.gov/pubmed/28244647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13085
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