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Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-β Signaling Through SMAD2 in a β-Catenin-Dependent Manner

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However, the role of the Wnt pathway in such settings remains unclear. In the current study, we treated mo...

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Detalhes bibliográficos
Main Authors: Carthy, Jon M., Garmaroudi, Farshid S., Luo, Zongshu, McManus, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097192/
https://ncbi.nlm.nih.gov/pubmed/21611174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019809
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