Duodenal ischemia and upper GI bleeding are dose-limiting toxicities of 24-hour continuous intra-arterial pancreatic perfusion of gemcitabine following vascular isolation of the pancreatic head: early results from the Regional Chemotherapy in Locally Advanced Pancreatic Cancer (RECLAP) study

BACKGROUND: Regional chemotherapy is used successfully in the treatment of both primary and secondary malignancies, in particular of the peritoneal surface and the liver, and is currently explored as an attractive approach for patients with locally advanced pancreatic ductal adenocarcinoma. To estab...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Beane, Joal D., Griffin, Kayla F., Levy, Elliot B., Pandalai, Prakash, Beresnev, Tatiana, Shutack, Yvonne, Webb, Carole C., Avital, Itzhak, Rudloff, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542811/
https://ncbi.nlm.nih.gov/pubmed/25236592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0157-7
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