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Quantitative Imaging Approaches to Study the CAR Immunological Synapse

The lytic immunological synapse (IS) is a discrete structural entity formed after the ligation of specific activating receptors that leads to the destruction of a cancerous cell. The formation of an effector cell IS in cytotoxic T lymphocytes or natural killer cells is a hierarchical and stepwise re...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Mukherjee, Malini, Mace, Emily M., Carisey, Alexandre F., Ahmed, Nabil, Orange, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542801/
https://ncbi.nlm.nih.gov/pubmed/28663103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.06.003
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