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A Novel Platform for Immune Tolerance Induction in Hemophilia A Mice

Hemophilia A (HA) is an X-linked bleeding disease caused by factor VIII (FVIII) deficiency. We previously demonstrated that FVIII is produced specifically in liver sinusoid endothelial cells (LSECs) and to some degree in myeloid cells, and thus, in the present work, we seek to restrict the expressio...

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Publicado en:Mol Ther
Main Authors: Merlin, Simone, Cannizzo, Elvira Stefania, Borroni, Ester, Bruscaggin, Valentina, Schinco, Piercarla, Tulalamba, Warut, Chuah, Marinee K., Arruda, Valder R., VandenDriessche, Thierry, Prat, Maria, Valente, Guido, Follenzi, Antonia
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542771/
https://ncbi.nlm.nih.gov/pubmed/28552407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.04.029
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