A Novel Platform for Immune Tolerance Induction in Hemophilia A Mice

Hemophilia A (HA) is an X-linked bleeding disease caused by factor VIII (FVIII) deficiency. We previously demonstrated that FVIII is produced specifically in liver sinusoid endothelial cells (LSECs) and to some degree in myeloid cells, and thus, in the present work, we seek to restrict the expressio...

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Опубликовано в: :Mol Ther
Главные авторы: Merlin, Simone, Cannizzo, Elvira Stefania, Borroni, Ester, Bruscaggin, Valentina, Schinco, Piercarla, Tulalamba, Warut, Chuah, Marinee K., Arruda, Valder R., VandenDriessche, Thierry, Prat, Maria, Valente, Guido, Follenzi, Antonia
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2017
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542771/
https://ncbi.nlm.nih.gov/pubmed/28552407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.04.029
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