A Novel Platform for Immune Tolerance Induction in Hemophilia A Mice

Hemophilia A (HA) is an X-linked bleeding disease caused by factor VIII (FVIII) deficiency. We previously demonstrated that FVIII is produced specifically in liver sinusoid endothelial cells (LSECs) and to some degree in myeloid cells, and thus, in the present work, we seek to restrict the expressio...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Merlin, Simone, Cannizzo, Elvira Stefania, Borroni, Ester, Bruscaggin, Valentina, Schinco, Piercarla, Tulalamba, Warut, Chuah, Marinee K., Arruda, Valder R., VandenDriessche, Thierry, Prat, Maria, Valente, Guido, Follenzi, Antonia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542771/
https://ncbi.nlm.nih.gov/pubmed/28552407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.04.029
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