Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface

Whooping cough, or pertussis, is a contagious disease of the respiratory tract that is re-emerging worldwide despite high vaccination coverage. The causative agent of this disease is the Gram-negative Bordetella pertussis. Knowledge on complement evasion strategies of this pathogen is limited. Howev...

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Pubblicato in:PLoS Pathog
Autori principali: Hovingh, Elise S., van den Broek, Bryan, Kuipers, Betsy, Pinelli, Elena, Rooijakkers, Suzan H. M., Jongerius, Ilse
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542704/
https://ncbi.nlm.nih.gov/pubmed/28742139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006531
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