Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor

Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries represent up to 95% of recent clinical isolates. Know...

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Publicat a:Emerg Microbes Infect
Autors principals: Hovingh, Elise Sofie, Mariman, Rob, Solans, Luis, Hijdra, Daniëlle, Hamstra, Hendrik-Jan, Jongerius, Ilse, van Gent, Marjolein, Mooi, Frits, Locht, Camille, Pinelli, Elena
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861065/
https://ncbi.nlm.nih.gov/pubmed/29559630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0039-8
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