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Targeting the unfolded protein response in cancer

Cancer cells are exposed to various intrinsic and extrinsic factors that disrupt protein homeostasis, producing endoplasmic reticulum (ER) stress. To cope with these situations, cancer cells evoke a highly conserved adaptive mechanism called the unfolded protein response (UPR) to restore the ER home...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res
Main Authors: Ojha, Rani, Amaravadi, Ravi K
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542584/
https://ncbi.nlm.nih.gov/pubmed/28396092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.04.003
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