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Targeting the unfolded protein response in cancer
Cancer cells are exposed to various intrinsic and extrinsic factors that disrupt protein homeostasis, producing endoplasmic reticulum (ER) stress. To cope with these situations, cancer cells evoke a highly conserved adaptive mechanism called the unfolded protein response (UPR) to restore the ER home...
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| Udgivet i: | Pharmacol Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5542584/ https://ncbi.nlm.nih.gov/pubmed/28396092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.04.003 |
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