Defective splicing of thyroglobulin gene transcripts in the congenital goitre of the Afrikander cattle.

The structure of thyroglobulin mRNA was analyzed in an inbred herd of Afrikander cattle with hereditary goitre. Northern transfer of RNA from affected animals revealed both a shorter (approximately 7100 bases) and a normal-sized (approximately 8200 bases) thyroglobulin mRNA when hybridized to bovine...

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Main Authors: Ricketts, M H, Pohl, V, de Martynoff, G, Boyd, C D, Bester, A J, Van Jaarsveld, P P, Vassart, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554249/
https://ncbi.nlm.nih.gov/pubmed/2988933
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