Congenital human thyroglobulin defect due to low expression of the thyroid-specific transcription factor TTF-1.

TTF-1 and Pax-8 are thyroid-specific transcription factors, from homeo and paired box genes, respectively, that are responsible for thyroid development and for thyroglobulin and thyroperoxidase gene expression. However, TTF-1 and Pax-8 preferentially bind to the thyroglobulin and thyroperoxidase pro...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Acebrón, A, Aza-Blanc, P, Rossi, D L, Lamas, L, Santisteban, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7635972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118123
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