C-abl and bcr are rearranged in a Ph1-negative CML patient.

Chromosomal analysis of a patient with chronic myelocytic leukemia (CML) revealed a translocation (9;12) (q34;q21) without a detectable Philadelphia chromosome (Ph1). Using molecular approaches we demonstrate (i) a rearrangement within the CML breakpoint cluster region (bcr) on chromosome 22, and (i...

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Autors principals: Bartram, C R, Kleihauer, E, de Klein, A, Grosveld, G, Teyssier, J R, Heisterkamp, N, Groffen, J
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC554242/
https://ncbi.nlm.nih.gov/pubmed/3859408
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