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Molecular analysis of both translocation products of a Philadelphia-positive CML patient.

The breakpoint regions of both translocation products of the (9;22) Philadelphia translocation of CML patient 83-H84 and their normal chromosome 9 and 22 counterparts have been cloned and analysed. Southern blotting with bcr probes and DNA sequencing revealed that the breaks on chromosome 22 occurre...

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Main Authors: de Klein, A, van Agthoven, T, Groffen, C, Heisterkamp, N, Groffen, J, Grosveld, G
Format: Artigo
Jezik:Inglês
Izdano: 1986
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC311718/
https://ncbi.nlm.nih.gov/pubmed/3463934
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