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The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia.

The hallmark of chronic myelogenous leukemia (CML) is a translocation between chromosomes 9 and 22 - the Philadelphia (Ph') translocation. The translocation is also found in acute lymphocytic leukemia (ALL) albeit in a lower percentage of patients. The breakpoint on chromosome 22 is located wit...

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Dettagli Bibliografici
Autori principali: Heisterkamp, N, Knoppel, E, Groffen, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC338837/
https://ncbi.nlm.nih.gov/pubmed/3194194
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