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5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression

High-risk human papillomaviruses are the etiological agents of cervical cancer and HPV16 is the most oncogenic genotype. Immortalization and transformation of infected cells requires the overexpression of the two viral oncoproteins E6 and E7 following HPV DNA integration into the host cell genome. I...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Morel, Adrien, Baguet, Aurélie, Perrard, Jérôme, Demeret, Caroline, Jacquin, Elise, Guenat, David, Mougin, Christiane, Prétet, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542257/
https://ncbi.nlm.nih.gov/pubmed/28521287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17575
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