DNA demethylation agent 5azadC downregulates HPV16 E6 expression in cervical cancer cell lines independently of TBX2 expression

HPV16 is the most carcinogenic human papillomavirus and causes >50% of cervical cancers, the majority of anal cancers and 30% of oropharyngeal squamous cell carcinomas. HPV carcinogenesis relies on the continuous expression of the two main viral oncoproteins E6 and E7 that target >150 cellular...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Perrard, Jerome, Morel, Adrien, Meznad, Koceila, Paget-Bailly, Philippe, Dalstein, Veronique, Guenat, David, Mourareau, Celine, Clavel, Christine, Fauconnet, Sylvie, Baguet, Aurelie, Mougin, Christiane, Pretet, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924136/
https://ncbi.nlm.nih.gov/pubmed/31897221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.11158
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