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ARID1B alterations identify aggressive tumors in neuroblastoma
Targeted panel sequencing was performed to determine molecular targets and biomarkers in 72 children with neuroblastoma. Frequent genetic alterations were detected in ALK (16.7%), BRCA1 (13.9%), ATM (12.5%), and PTCH1 (11.1%) in an 83-gene panel. Molecular targets for targeted therapy were identifie...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5542239/ https://ncbi.nlm.nih.gov/pubmed/28521285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17500 |
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