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ARID1B alterations identify aggressive tumors in neuroblastoma

Targeted panel sequencing was performed to determine molecular targets and biomarkers in 72 children with neuroblastoma. Frequent genetic alterations were detected in ALK (16.7%), BRCA1 (13.9%), ATM (12.5%), and PTCH1 (11.1%) in an 83-gene panel. Molecular targets for targeted therapy were identifie...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Lee, Soo Hyun, Kim, Jung-Sun, Zheng, Siyuan, Huse, Jason T., Bae, Joon Seol, Lee, Ji Won, Yoo, Keon Hee, Koo, Hong Hoe, Kyung, Sungkyu, Park, Woong-Yang, Sung, Ki W.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542239/
https://ncbi.nlm.nih.gov/pubmed/28521285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17500
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