An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

The incidence of pediatric adrenal cortical carcinoma (ACC) in southern Brazil is 10–15 times higher than that of pediatric ACC worldwide. Because childhood ACC is associated with Li-Fraumeni syndrome, we examined the cancer history and p53 status of 36 Brazilian patients and their families. Remarka...

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Main Authors: Ribeiro, Raul C., Sandrini, Fabiano, Figueiredo, Bonald, Zambetti, Gerard P., Michalkiewicz, Edson, Lafferty, Antony R., DeLacerda, Luiz, Rabin, Mark, Cadwell, Craig, Sampaio, Gilberto, Cat, Israil, Stratakis, Constantine A., Sandrini, Romolo
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC55420/
https://ncbi.nlm.nih.gov/pubmed/11481490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161479898
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