An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

The incidence of pediatric adrenal cortical carcinoma (ACC) in southern Brazil is 10–15 times higher than that of pediatric ACC worldwide. Because childhood ACC is associated with Li-Fraumeni syndrome, we examined the cancer history and p53 status of 36 Brazilian patients and their families. Remarka...

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Autors principals: Ribeiro, Raul C., Sandrini, Fabiano, Figueiredo, Bonald, Zambetti, Gerard P., Michalkiewicz, Edson, Lafferty, Antony R., DeLacerda, Luiz, Rabin, Mark, Cadwell, Craig, Sampaio, Gilberto, Cat, Israil, Stratakis, Constantine A., Sandrini, Romolo
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55420/
https://ncbi.nlm.nih.gov/pubmed/11481490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161479898
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