An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

The incidence of pediatric adrenal cortical carcinoma (ACC) in southern Brazil is 10–15 times higher than that of pediatric ACC worldwide. Because childhood ACC is associated with Li-Fraumeni syndrome, we examined the cancer history and p53 status of 36 Brazilian patients and their families. Remarka...

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Detalhes bibliográficos
Main Authors: Ribeiro, Raul C., Sandrini, Fabiano, Figueiredo, Bonald, Zambetti, Gerard P., Michalkiewicz, Edson, Lafferty, Antony R., DeLacerda, Luiz, Rabin, Mark, Cadwell, Craig, Sampaio, Gilberto, Cat, Israil, Stratakis, Constantine A., Sandrini, Romolo
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55420/
https://ncbi.nlm.nih.gov/pubmed/11481490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161479898
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