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Chemotherapeutic xCT inhibitors sorafenib and erastin unraveled with the synaptic optogenetic function analysis tool

In the search for new potential chemotherapeutics, the compounds’ toxicity to healthy cells is an important factor. The brain with its functional units, the neurons, is especially endangered during the radio- and chemotherapeutic treatment of brain tumors. The effect of the potential compounds not o...

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Bibliografiska uppgifter
I publikationen:Cell Death Discov
Huvudupphovsmän: Dahlmanns, Marc, Yakubov, Eduard, Chen, Daishi, Sehm, Tina, Rauh, Manfred, Savaskan, Nicolai, Wrosch, Jana Katharina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541984/
https://ncbi.nlm.nih.gov/pubmed/28835855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.30
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