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Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation

Motor neuron (MN) diseases are progressive disorders resulting from degeneration of neuromuscular junctions (NMJs), which form the connection between MNs and muscle fibers. NMJ-in-a-dish models have been developed to examine human MN-associated dysfunction with disease; however such coculture models...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Happe, Cassandra L., Tenerelli, Kevin P., Gromova, Anastasia K., Kolb, Frederic, Engler, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541845/
https://ncbi.nlm.nih.gov/pubmed/28495800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0046
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