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Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction

A prominent feature of synaptic maturation at the neuromuscular junction (NMJ) is the topological transformation of the acetylcholine receptor (AChR)-rich postsynaptic membrane from an ovoid plaque into a complex array of branches. We show here that laminins play an autocrine role in promoting this...

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Autors principals: Nishimune, Hiroshi, Valdez, Gregorio, Jarad, George, Moulson, Casey L., Müller, Ulrich, Miner, Jeffrey H., Sanes, Joshua R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542479/
https://ncbi.nlm.nih.gov/pubmed/18794334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805095
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