Aspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma

The mechanism of aberrant mitochondrial genome and function in hepatocellular carcinoma (HCC) remains largely unknown. Our previous study demonstrated an increased expression of aspartate β-hydroxylase (ASPH) in HCC tissues, which was associated with tumor invasiveness and a worse prognosis. Current...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Tang, C, Hou, Y, Wang, H, Wang, K, Xiang, H, Wan, X, Xia, Y, Li, J, Wei, W, Xu, S, Lei, Z, Pawlik, T M, Wu, M, Shen, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541716/
https://ncbi.nlm.nih.gov/pubmed/28714949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.64
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