Aspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma

The mechanism of aberrant mitochondrial genome and function in hepatocellular carcinoma (HCC) remains largely unknown. Our previous study demonstrated an increased expression of aspartate β-hydroxylase (ASPH) in HCC tissues, which was associated with tumor invasiveness and a worse prognosis. Current...

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Bibliografiske detaljer
Udgivet i:	Oncogenesis
Main Authors:	Tang, C, Hou, Y, Wang, H, Wang, K, Xiang, H, Wan, X, Xia, Y, Li, J, Wei, W, Xu, S, Lei, Z, Pawlik, T M, Wu, M, Shen, F
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2017
Fag:	Original Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5541716/ https://ncbi.nlm.nih.gov/pubmed/28714949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.64
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Aspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma

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