JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells

Platinum chemotherapeutics are widely used to treat solid malignant tumors, including gastric cancer (GC). Drug resistance to platinum compounds may result in cancer relapse and decreased survival. The identification and development of novel agents to reactivate apoptosis pathways in platinum-resist...

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Publicat a:Oncogenesis
Autors principals: Wang, Q, Chen, Q, Zhu, L, Chen, M, Xu, W, Panday, S, Wang, Z, Li, A, Røe, O D, Chen, R, Wang, S, Zhang, R, Zhou, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541709/
https://ncbi.nlm.nih.gov/pubmed/28671676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.57
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