Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis

BACKGROUND: Drug resistance is a major problem in ovarian cancer. Triggering apoptosis using death ligands such as tumour necrosis factor-related apoptosis inducing ligand (TRAIL) might overcome chemoresistance. METHODS: We investigated whether acquired cisplatin resistance affects sensitivity to re...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Duiker, E W, Meijer, A, van der Bilt, A R M, Meersma, G J, Kooi, N, van der Zee, A G J, de Vries, E G, de Jong, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078595/
https://ncbi.nlm.nih.gov/pubmed/21487429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.84
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker