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Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization

BACKGROUND: Human cancer cell lines are used in research to study the biology of cancer and to test cancer treatments. Recently there are already some large panels of several hundred human cancer cell lines which are characterized with genomic and pharmacological data. The ability to predict drug re...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Wang, Lin, Li, Xiaozhong, Zhang, Louxin, Gao, Qiang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541434/
https://ncbi.nlm.nih.gov/pubmed/28768489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3500-5
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