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Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization

BACKGROUND: Human cancer cell lines are used in research to study the biology of cancer and to test cancer treatments. Recently there are already some large panels of several hundred human cancer cell lines which are characterized with genomic and pharmacological data. The ability to predict drug re...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Wang, Lin, Li, Xiaozhong, Zhang, Louxin, Gao, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541434/
https://ncbi.nlm.nih.gov/pubmed/28768489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3500-5
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