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PiiL: visualization of DNA methylation and gene expression data in gene pathways

BACKGROUND: DNA methylation is a major mechanism involved in the epigenetic state of a cell. It has been observed that the methylation status of certain CpG sites close to or within a gene can directly affect its expression, either by silencing or, in some cases, up-regulating transcription. However...

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Pubblicato in:BMC Genomics
Autori principali: Moghadam, Behrooz Torabi, Zamani, Neda, Komorowski, Jan, Grabherr, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541427/
https://ncbi.nlm.nih.gov/pubmed/28768481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3950-9
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