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Functional Mu Opioid Receptor Polymorphism (OPRM1 A(118)G) Associated With Heroin Use Outcomes in Caucasian Males: A Pilot Study
BACKGROUND: Heroin’s analgesic, euphoric and dependence-producing effects are primarily mediated by the mu opioid receptor (MOR). A single gene, OPRM1, encodes the MOR. The functional polymorphism A(118)G, located in exon 1 of the OPRM1 gene, results in anatomically-specific reductions in MOR expres...
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| Veröffentlicht in: | Am J Addict |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5541380/ https://ncbi.nlm.nih.gov/pubmed/25911999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajad.12187 |
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