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The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA repair factors in infected cells
Human papillomaviruses (HPV) exhibit constitutive activation of ATM and ATR DNA damage response (DDR) pathways, which are required for productive viral replication. Expression of HPV31 E7 alone is sufficient to activate the DDR through an unknown mechanism. Here, we demonstrate that the E7 Rb bindin...
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| Publicat a: | Virology |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5541366/ https://ncbi.nlm.nih.gov/pubmed/27770701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.09.029 |
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