Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31

High-risk human papillomavirus 31 (HPV31)-positive cells exhibit constitutive activation of the ATM-dependent DNA damage response (DDR), which is necessary for productive viral replication. In response to DNA double-strand breaks (DSBs), ATM activation leads to DNA repair through homologous recombin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chappell, William H., Gautam, Dipendra, Ok, Suzan T., Johnson, Bryan A., Anacker, Daniel C., Moody, Cary A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810724/
https://ncbi.nlm.nih.gov/pubmed/26699641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02495-15
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