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Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1
Hsp70 chaperones mediate folding of proteins and prevent their misfolding and aggregation. We report here on a new kind of Hsp70 interacting protein in mitochondria, Hep1. Hep1 is a highly conserved protein present in virtually all eukaryotes. Deletion of HEP1 results in a severe growth defect. Cell...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554129/ https://ncbi.nlm.nih.gov/pubmed/15719019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600580 |
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