Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1

Hsp70 chaperones mediate folding of proteins and prevent their misfolding and aggregation. We report here on a new kind of Hsp70 interacting protein in mitochondria, Hep1. Hep1 is a highly conserved protein present in virtually all eukaryotes. Deletion of HEP1 results in a severe growth defect. Cell...

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Bibliografski detalji

Izdano u:	EMBO J
Glavni autori:	Sichting, Martin, Mokranjac, Dejana, Azem, Abdussalam, Neupert, Walter, Hell, Kai
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2005
Teme:	Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15719019/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600580
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