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Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway

The key molecular mechanism governing the cancer cell state (stem cell-like state vs differentiation state) to control the cancer stem cell (CSC) pool remains elusive. This study provides the first evidence showing that all-trans retinoic acid (ATRA) induces the interaction and chromatin recruitment...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wu, M-J, Kim, M R, Chen, Y-S, Yang, J-Y, Chang, C-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541263/
https://ncbi.nlm.nih.gov/pubmed/28218902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.467
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