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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

BACKGROUND: Mammalian cells have been reported to have a p53-dependent tetraploidy checkpoint that blocks cell cycle progression in G1 in response to failure of cell division. In most cases where the tetraploidy checkpoint has been observed cell division was perturbed by anti-cytoskeleton drug treat...

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Bibliografski detalji
Izdano u:BMC Cell Biol
Glavni autori: Wong, Connie, Stearns, Tim
Format: Artigo
Jezik:Inglês
Izdano: BMC 2005
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-6-6
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