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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

BACKGROUND: Mammalian cells have been reported to have a p53-dependent tetraploidy checkpoint that blocks cell cycle progression in G1 in response to failure of cell division. In most cases where the tetraploidy checkpoint has been observed cell division was perturbed by anti-cytoskeleton drug treat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cell Biol
Prif Awduron: Wong, Connie, Stearns, Tim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-6-6
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