Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx

Castration resistant prostate cancer (CRPC) has greater intratumoral testosterone concentrations than similar tumors from eugonadal men; simple diffusion does not account for this observation. The present study was undertaken to ascertain the androgen uptake kinetics, functional, and clinical releva...

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Udgivet i:Mol Cancer Res
Main Authors: Sissung, Tristan M., Ley, Ariel M., Strope, Jonathan D., McCrea, Edel M., Beedie, Shaunna, Peer, Cody J., Shukla, Suneet, van Velkinburgh, Jennifer, Reece, Kelie, Troutman, Sarah, Campbell, Tessa, Fernandez, Elena, Huang, Phoebe, Smith, Jordan, Thakkar, Nilay, Venzon, David J., Brenner, Stefan, Lee, Wooin, Merino, Maria, Luo, Ji, Jager, Walter, Price, Douglas K., Chau, Cindy H., Figg, William D.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540879/
https://ncbi.nlm.nih.gov/pubmed/28389619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0477
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