Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx

Castration resistant prostate cancer (CRPC) has greater intratumoral testosterone concentrations than similar tumors from eugonadal men; simple diffusion does not account for this observation. The present study was undertaken to ascertain the androgen uptake kinetics, functional, and clinical releva...

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Gepubliceerd in:Mol Cancer Res
Hoofdauteurs: Sissung, Tristan M., Ley, Ariel M., Strope, Jonathan D., McCrea, Edel M., Beedie, Shaunna, Peer, Cody J., Shukla, Suneet, van Velkinburgh, Jennifer, Reece, Kelie, Troutman, Sarah, Campbell, Tessa, Fernandez, Elena, Huang, Phoebe, Smith, Jordan, Thakkar, Nilay, Venzon, David J., Brenner, Stefan, Lee, Wooin, Merino, Maria, Luo, Ji, Jager, Walter, Price, Douglas K., Chau, Cindy H., Figg, William D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540879/
https://ncbi.nlm.nih.gov/pubmed/28389619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0477
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