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Dendritic cells that phagocytose apoptotic macrophages loaded with mycobacterial antigens activate CD8 T cells via cross-presentation

While homeostatic apoptosis is immunologically silent, macrophage apoptosis during Mycobacterium tuberculosis infection can potentially induce an immune response against the mycobacteria. To examine the role of dendritic cells in this response, macrophage apoptosis was induced by incubating the macr...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Espinosa-Cueto, Patricia, Magallanes-Puebla, Alejandro, Castellanos, Carlos, Mancilla, Raul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540487/
https://ncbi.nlm.nih.gov/pubmed/28767693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182126
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