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Dendritic cells that phagocytose apoptotic macrophages loaded with mycobacterial antigens activate CD8 T cells via cross-presentation

While homeostatic apoptosis is immunologically silent, macrophage apoptosis during Mycobacterium tuberculosis infection can potentially induce an immune response against the mycobacteria. To examine the role of dendritic cells in this response, macrophage apoptosis was induced by incubating the macr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Espinosa-Cueto, Patricia, Magallanes-Puebla, Alejandro, Castellanos, Carlos, Mancilla, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540487/
https://ncbi.nlm.nih.gov/pubmed/28767693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182126
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