Dendritic cells that phagocytose apoptotic macrophages loaded with mycobacterial antigens activate CD8 T cells via cross-presentation

While homeostatic apoptosis is immunologically silent, macrophage apoptosis during Mycobacterium tuberculosis infection can potentially induce an immune response against the mycobacteria. To examine the role of dendritic cells in this response, macrophage apoptosis was induced by incubating the macr...

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Bibliographic Details
Published in:PLoS One
Main Authors: Espinosa-Cueto, Patricia, Magallanes-Puebla, Alejandro, Castellanos, Carlos, Mancilla, Raul
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540487/
https://ncbi.nlm.nih.gov/pubmed/28767693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182126
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