Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells

PURPOSE: To investigate the effect of rho kinase inhibitors on oxidative stress in trabecular meshwork (TM) cells. METHODS: TM cells were isolated from the eyes of cynomolgus monkeys. Y-27632 and menadione were used to inhibit rho kinase and induce production of reactive oxygen species (ROS), respec...

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Detalhes bibliográficos
Publicado no:J Ophthalmol
Main Authors: Fujimoto, Tomokazu, Inoue, Toshihiro, Ohira, Saori, Awai-Kasaoka, Nanako, Kameda, Takanori, Inoue-Mochita, Miyuki, Tanihara, Hidenobu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540245/
https://ncbi.nlm.nih.gov/pubmed/28804648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7598140
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