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Real-Time Detection of Cellular Death Receptor-4 Activation by Fluorescence Resonance Energy Transfer
Targeted therapy involving the activation of death receptors DR4 and/or DR5 by its ligand, TRAIL, can selectively induce apoptosis in certain tumor cells. In order to profile the dynamic activation or trimerization of TRAIL-DR4 in live cells in real time, the development of an apoptosis reporter cel...
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| Publicado no: | Biotechnol Bioeng |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540232/ https://ncbi.nlm.nih.gov/pubmed/23239419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24804 |
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