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Dual epigenetic modifiers for cancer therapy

Epigenetic drug discovery is an emerging strategy for the treatment of cancer and other pathologies. Here, we discuss our recent discovery of first-in-class dual reversible inhibitors of the histone methyltransferase activity of G9a/EHMT2 and DNA methyltransferases showing in vivo efficacy in human...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: José-Enériz, Edurne San, Rabal, Obdulia, Agirre, Xabier, Oyarzabal, Julen, Prosper, Felipe
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540207/
https://ncbi.nlm.nih.gov/pubmed/28868353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1342748
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