Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest

The Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a major mediator of physiological glutamate signaling, but its role in pathological glutamate signaling (excitotoxicity) remains less clear, with indications for both neurotoxic and neuro-protective functions. Here, the role of CaMKII in...

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Publicado no:Cell Rep
Main Authors: Deng, Guiying, Orfila, James E., Dietz, Robert M., Moreno-Garcia, Myriam, Rodgers, Krista M., Coultrap, Steve J., Quillinan, Nidia, Traystman, Richard J., Bayer, K. Ulrich, Herson, Paco S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540152/
https://ncbi.nlm.nih.gov/pubmed/28147268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.011
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