CCAAT/enhancer binding protein β deletion increases mitochondrial function and protects mice from LXR-induced hepatic steatosis

Drugs designed specifically to activate liver X receptors (LXRs) have beneficial effects on lowering cholesterol metabolism and inflammation but unfortunately lead to severe hepatic steatosis. The transcription factor CCAAT/enhancer binding protein beta (C/EBPβ) is an important regulator of liver ge...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Rahman, Shaikh M., Choudhury, Mahua, Janssen, Rachel C., Baquero, Karalee C., Miyazaki, Makoto, Friedman, Jacob E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540138/
https://ncbi.nlm.nih.gov/pubmed/23159614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.027
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge