CCAAT/enhancer binding protein β deletion increases mitochondrial function and protects mice from LXR-induced hepatic steatosis

Drugs designed specifically to activate liver X receptors (LXRs) have beneficial effects on lowering cholesterol metabolism and inflammation but unfortunately lead to severe hepatic steatosis. The transcription factor CCAAT/enhancer binding protein beta (C/EBPβ) is an important regulator of liver ge...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Rahman, Shaikh M., Choudhury, Mahua, Janssen, Rachel C., Baquero, Karalee C., Miyazaki, Makoto, Friedman, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540138/
https://ncbi.nlm.nih.gov/pubmed/23159614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.027
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