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Nickel Ligation of the N-terminal Amine of HypA is required for urease maturation in Helicobacter pylori

The human pathogen Helicobacter pylori requires nickel for colonization of the acidic environment of the stomach. HypA, a Ni metallochaperone that is typically associated with hydrogenase maturation, is also required for urease maturation and acid survival of H. pylori. There are two proposed Ni sit...

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Pubblicato in:Biochemistry
Autori principali: Hu, Heidi Q., Johnson, Ryan C., Merrell, D. Scott, Maroney, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540134/
https://ncbi.nlm.nih.gov/pubmed/28177601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00912
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